Why would anion gap be low?
Acidosis may be a sign of dehydration, diarrhea, or too much exercise.
It may also indicate a more serious condition such as kidney disease or diabetes.
If your results show a low anion gap, it may mean you have a low level of albumin, a protein in the blood.
How is low anion gap treated?
Lithium is positively charged and is sometimes prescribed for treatment of bipolar disorder. In high concentrations, it can lower the anion gap. Increase in other positively charged ions. A large increase in other positively charged ions, such as calcium and magnesium, can also lower the anion gap.
What are symptoms of low anion gap?
A person with acidosis may not experience any symptoms or may have nonspecific symptoms related to the underlying medical condition, such as:
- nausea or vomiting.
- a headache.
- shortness of breath.
- rapid heart rate.
- low blood pressure.
Why is anion gap important?
It is important because an increased anion gap usually is caused by an increase in unmeasured anions, and that most commonly occurs when there is an increase in unmeasured organic acids, that is, an acidosis3, 4). Acids (eg, lactate and pyruvate) are protons donors and must be buffered by bicarbonate.